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m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01011 | -- | $-- | Inquiry |
mPEG6-amine, a polyethylene glycol molecule featuring an amine group, showcases exceptional versatility in bioconjugation and drug delivery applications.
Drug Delivery Systems: The widespread integration of mPEG6-amine in formulating drug delivery systems underscores its pivotal role in augmenting the solubility and stability of therapeutic agents. By coupling drugs with mPEG6-amine, pharmaceutical entities can enhance drug pharmacokinetics and mitigate immunogenic responses.
Protein Modification: Within the domain of protein engineering, mPEG6-amine emerges as a coveted reagent for PEGylation, a transformative process entailing the attachment of polyethylene glycol chains to proteins. This modification confers heightened protein stability, reduced immunogenicity, and prolonged protein half-life within the physiological milieu. The amine moiety of mPEG6-amine facilitates precise and efficient protein surface conjugation, establishing it as an indispensable tool in the realm of therapeutic protein advancement.
Diagnostic Imaging: Harnessing mPEG6-amine for enhancing imaging agents serves as a testament to its profound impact on biocompatibility and circulation duration. Through the linkage of mPEG6-amine to imaging moieties, researchers can amplify the contrast and specificity of diagnostic instruments in medical imaging modalities like MRI and PET scans. This application assumes a pivotal role in ensuring precise disease diagnosis by yielding vivid and accurate imaging results.
Surface Modification: In the dynamic arena of biomaterials science, mPEG6-amine finds extensive utilization in surface modification initiatives pertaining to medical devices and implants. By coating surfaces with mPEG6-amine, researchers can effectively mitigate biofouling occurrences and cultivate enhanced biocompatibility. This strategic surface alteration hampers protein adsorption and cellular attachment, thereby reducing the risk of infection and inflammation.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
