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m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | |
|---|---|---|---|---|
| BADC-01177 | -- | $-- | Inquiry |
mPEG8-amine, a derivative of polyethylene glycol, boasts unique properties that make it a versatile choice for diverse biomedical and chemical applications. Explore four key applications of mPEG8-amine:
Drug Delivery: Powering the advancement of drug delivery systems, mPEG8-amine is instrumental in enhancing the solubility and stability of pharmaceutical compounds. Through the strategic conjugation of drugs with mPEG8-amine, researchers can extend their circulation time and mitigate immunogenicity, ultimately revolutionizing drug delivery efficiency and elevating therapeutic outcomes to new heights.
Bioconjugation: In the intricate domain of bioconjugation, mPEG8-amine emerges as a crucial player, facilitating the modification of proteins, peptides, and other biomolecules. Leveraging its amine functional group, mPEG8-amine enables stable covalent attachment to diverse targets, amplifying their solubility and biocompatibility. This crucial modification serves as a catalyst for enhancing the pharmacokinetics and efficacy of biologically active compounds.
Surface Modification: Delving into surface modification applications, mPEG8-amine takes center stage in the coating of medical devices and nanoparticles. By grafting mPEG8-amine onto surfaces, a hydrophilic layer is crafted, curbing protein adsorption and cell adhesion. This quality is pivotal in sculpting biocompatible surfaces that mitigate immune responses and optimize implant performance.
Diagnostics: Stepping into the realm of diagnostics, mPEG8-amine assumes a crucial role in steering the development of imaging agents and biosensors. The versatility of mPEG8-amine in conjugating with an array of probes or markers facilitates the creation of targeted diagnostics with exquisite specificity and sensitivity.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
