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2, 5-Dioxopyrrolidin-1-yl 1-bromo-3-methyl-2-oxo-6, 9, 12, 15-tetraoxa-3-azaoctadecan-18-oate is a linker for antibody-drug-conjugation (ADC).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00577 | -- | $-- |
2,5-Dioxopyrrolidin-1-Yl 1-Bromo-3-Methyl-2-Oxo-6,9,12,15-Tetraoxa-3-Azaoctadecan-18-Oate, commonly known as a versatile organic compound, finds extensive application in the field of medicinal chemistry. One of its key uses is in the synthesis of peptide-based drugs. This compound acts as a crucial building block in the formation of complex peptide chains, enhancing the potency and efficacy of therapeutic peptides. By facilitating the creation of stable and bioactive peptide structures, it plays a significant role in the development of novel therapeutics for various diseases, including cancer and infectious diseases.
In the realm of biochemical research, 2,5-Dioxopyrrolidin-1-Yl 1-Bromo-3-Methyl-2-Oxo-6,9,12,15-Tetraoxa-3-Azaoctadecan-18-Oate serves as an important reagent for protein modification. Its unique structure enables the bromination and subsequent functionalization of protein molecules, allowing scientists to study protein interactions and functions more precisely. This capability is particularly valuable in proteomics and molecular biology, where understanding protein dynamics is essential for discovering new biomarkers and therapeutic targets.
The compound also has significant applications in the development of drug delivery systems. Due to its ability to form stable linkages with various drug molecules, it is employed in creating prodrugs and targeted delivery vehicles. These applications improve the bioavailability and therapeutic index of drugs, ensuring that the active pharmaceutical ingredients are delivered effectively to the target sites within the body. Consequently, it aids in minimizing side effects and increasing the efficacy of treatments for a range of ailments.
Furthermore, 2,5-Dioxopyrrolidin-1-Yl 1-Bromo-3-Methyl-2-Oxo-6,9,12,15-Tetraoxa-3-Azaoctadecan-18-Oate is utilized in organic synthesis as a coupling agent. Its ability to facilitate the formation of covalent bonds between different organic molecules makes it a valuable tool in the synthesis of complex organic compounds. This application is particularly important in the field of materials science, where the creation of new materials with unique properties is essential for technological advancements. By enabling the synthesis of novel polymers and advanced materials, it contributes to the development of innovative solutions in various industries, including electronics, pharmaceuticals, and nanotechnology.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
