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Amino-PEG4-bis-PEG3-propargyl is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01213 | -- | $-- |
Amino-PEG4-bis-PEG3-propargyl, a versatile compound renowned for its singular properties, finds extensive utility in diverse biochemical and biotechnological realms. Delve into four key applications of Amino-PEG4-bis-PEG3-propargyl, presented with a high degree of perplexity and burstiness:
Bioconjugation: A cornerstone of bioconjugation reactions, Amino-PEG4-bis-PEG3-propargyl acts as a pivotal linkage agent for biomolecules such as proteins, peptides, and antibodies. The propargyl group's prowess in click chemistry reactions enables precise and efficient conjugation, fostering the creation of sophisticated molecular probes and targeted drug delivery systems that promise heightened efficacy and precision.
Surface Functionalization: Embracing diverse surface modification applications, this compound revolutionizes biosensors and medical devices. By grafting Amino-PEG4-bis-PEG3-propargyl onto surfaces, a biocompatible and antifouling shield forms, curtailing nonspecific binding and boosting sensor performance. This tailored surface augmentation uplifts the sensitivity and specificity of diagnostic tools, promising enhanced precision in diagnostics and monitoring.
Drug Delivery: At the forefront of drug delivery system design, Amino-PEG4-bis-PEG3-propargyl takes center stage in enhancing drug solubility, stability, and bioavailability. Through adept drug conjugation with this compound, prodrug formulations emerge that orchestrate controlled release of active agents, amplifying drug efficacy while quelling side effects. This strategic approach heralds a new era of refined therapeutics, balancing potency and safety.
Nanoparticle Functionalization: In the dynamic realm of nanotechnology, Amino-PEG4-bis-PEG3-propargyl assumes a crucial role in nanoparticle functionalization for targeted delivery and precise imaging applications. Leveraging PEGylation, these nanoparticles boast prolonged circulation in the bloodstream and diminished immunogenicity, rendering them paramount for targeted cancer therapy and diagnostic imaging, promising advanced precision and efficacy in disease management and detection.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
