Catalog Number | Size | Price | Quantity | ||
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BADC-01220 | -- | $-- | Inquiry |
Azido-PEG1-Val-Cit-OH, a versatile linker compound utilized in bioconjugation and drug delivery systems, finds diverse applications. Here are four key applications:
Antibody-Drug Conjugates (ADCs): Employing Azido-PEG1-Val-Cit-OH as a pivotal linker in ADC synthesis, researchers craft targeted therapies for cancer by merging antibodies with cytotoxic drugs. This sophisticated linker ensures steadfast attachment of the drug to the antibody, enabling controlled release upon binding to the cancer cell target.
Proteomics: Within the realm of proteomics research, Azido-PEG1-Val-Cit-OH serves as a valuable tool for labeling proteins with fluorescent tags or other probes. This labeling strategy enables scrutiny of protein interactions, modifications, and functions within intricate biological systems. The cleavable nature of the linker facilitates the isolation of labeled proteins, paving the way for in-depth analysis and deeper insights into cellular processes.
Site-Specific Bioconjugation: Azido-PEG1-Val-Cit-OH facilitates precise bioconjugation through “click chemistry,” a bio-orthogonal reaction enabling targeted attachment of therapeutic agents, imaging probes, or functional molecules to specific biomolecules. This unparalleled specificity is essential for the development of precision-targeted therapies and advanced diagnostic tools.
Drug Delivery Systems: Fostering innovation in drug delivery systems, Azido-PEG1-Val-Cit-OH plays a pivotal role in designing sophisticated nanoparticles and polymer-drug conjugates. This versatile linker ensures stable drug incorporation within the delivery vehicle, enabling controlled release in response to specific cellular cues. By enhancing drug solubility, bioavailability, and targeted delivery to diseased tissues, this approach revolutionizes drug delivery, promising optimized therapeutic outcomes.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.