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| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01038 | -- | $-- | Inquiry |
Azido-PEG4-Val-Cit-PAB-OH, a versatile linker molecule widely employed in bioconjugation and drug development, boasts diverse applications across various fields. Here are four key applications presented with a high degree of perplexity and burstiness:
Antibody-Drug Conjugates (ADCs): Positioned at the forefront of ADC synthesis, this molecule plays a pivotal role in advanced targeted cancer therapies that merge antibodies with cytotoxic drugs. The PEG4 spacer offers flexibility and improved solubility, while the Val-Cit cleavable linker ensures precise drug release within the tumor microenvironment. This intricate design facilitates the targeted delivery of potent drugs to cancer cells, minimizing off-target effects and maximizing therapeutic efficacy.
Protein-Protein Conjugation: Serving as a cornerstone in biotechnological applications like biosensors and protein-based therapies, this versatile linker enables the conjugation of proteins to diverse molecules or surfaces. The azido group allows for site-specific attachment through click chemistry, ensuring stable and efficient conjugation processes. This innovative technique drives the development of novel biomaterials and therapeutic proteins, catalyzing advancements in biotechnology.
Drug Delivery Research: Functioning as a key player in the design of drug delivery systems such as nanoparticles and liposomes, Azido-PEG4-Val-Cit-PAB-OH aims to enhance targeting and controlled release of therapeutic agents. The PEG spacer enhances biocompatibility and circulation time, while the cleavable linker guarantees precise drug release at the designated site. This approach significantly improves efficacy and minimizes side effects associated with a wide range of pharmaceuticals, paving the way for enhanced patient outcomes.
Diagnostic Imaging: In the domain of diagnostic imaging, this molecule assumes a crucial role in conjugating imaging agents to specific targeting moieties, revolutionizing medical diagnostics. The azido group facilitates the attachment of imaging agents to target proteins or peptides, enabling precise imaging of intricate biological processes. This capability proves invaluable in tracking disease progression and evaluating therapeutic intervention effectiveness, underscoring its critical role in advancing diagnostic imaging techniques.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
