DBCO-PEG3-TCO

DBCO-PEG3-TCO Catalog number: BADC-01246

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category
ADCs Linker
Product Name
DBCO-PEG3-TCO
Catalog Number
BADC-01246
Molecular Formula
C36H45N3O7
Molecular Weight
631.76

Ordering Information

Catalog Number Size Price Quantity
BADC-01246 -- $--
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Canonical SMILES
C1CC=CCCC(C1)OC(=O)NCCOCCOCCOCCNC(=O)CCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42
InChI
InChI=1S/C36H45N3O7/c40-34(18-19-35(41)39-28-31-12-7-6-10-29(31)16-17-30-11-8-9-15-33(30)39)37-20-22-43-24-26-45-27-25-44-23-21-38-36(42)46-32-13-4-2-1-3-5-14-32/h1-2,6-12,15,32H,3-5,13-14,18-28H2,(H,37,40)(H,38,42)/b2-1+/t32-/m1/s1
InChIKey
OYEIJQBQBCHZLD-XIASJIJZSA-N
Solubility
10 mm in DMSO
Appearance
Light yellow oil
Purity
98.0%
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20 °C, keep in dry and avoid sunlight.

DBCO-PEG3-TCO, a versatile bioconjugation reagent, offers functionalities tailored for efficient click chemistry applications. Here are four key applications of DBCO-PEG3-TCO:

Bioorthogonal Chemistry: Playing a pivotal role in bioorthogonal reactions, DBCO-PEG3-TCO enables the precise modification of biomolecules at specific sites, all while maintaining the integrity of natural cellular processes. Researchers utilize this reagent to tag proteins, nucleic acids, and other biomolecules in a remarkably specific manner. This technique proves invaluable for dissecting dynamic biological processes within live cells and organisms.

Therapeutic Development: In the realm of drug delivery and therapeutic advancement, DBCO-PEG3-TCO emerges as a key player. It facilitates the conjugation of therapeutic agents with targeted ligands or antibodies, ensuring the precise delivery of drugs to designated cells or tissues. Such targeted delivery not only enhances therapeutic effectiveness but also mitigates off-target effects and toxicity.

Diagnostics: DBCO-PEG3-TCO finds application in diagnostic imaging and assay development, revolutionizing the visualization and detection of specific cellular components or disease markers. By attaching imaging agents or probes to biomolecules of interest, this reagent aids in accurate diagnosis and monitoring of disease progression. Its role in diagnostic precision is paramount for improving patient outcomes and treatment strategies.

Biomolecular Engineering: Powering biomolecular innovation across research and industry, DBCO-PEG3-TCO enables the precise conjugation of functional groups, leading to the creation of novel biomaterials and enzymes with enhanced properties.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: DBCO-PEG3-TCO
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