Catalog Number | Size | Price | Quantity |
---|---|---|---|
BADC-01248 | -- | $-- |
DBCO-PEG4-alkyne is a versatile compound widely used in bioorthogonal chemistry and bioconjugation applications. Here are some key applications of DBCO-PEG4-alkyne:
1. Protein Labeling: DBCO-PEG4-alkyne is commonly utilized in the selective labeling of proteins through click chemistry. By reacting with azide-tagged proteins, it allows for the efficient attachment of various probes and labels. This application is essential for studying protein interactions and localizations in live cells.
2. Drug Delivery Systems: DBCO-PEG4-alkyne can be employed in the design of targeted drug delivery systems. By conjugating therapeutic agents with DBCO-PEG4-alkyne, drugs can be selectively delivered to azide-modified cells or tissues. This ensures higher specificity and reduced side effects in therapeutic interventions.
3. Nanomaterial Functionalization: DBCO-PEG4-alkyne is used to functionalize nanoparticles with specific ligands or molecules. It enables the attachment of azide-functionalized biomolecules to the surface of nanoparticles, enhancing their targeting capability and functionality. This application is pivotal in the development of advanced diagnostic and therapeutic nanomedicines.
4. Surface Chemistry and Biomaterial Engineering: DBCO-PEG4-alkyne is vital in surface modification of biomaterials to introduce bioactive molecules. By grafting azide-containing molecules onto material surfaces, it facilitates the covalent attachment through click reactions. This improves the biocompatibility and functionality of implants and scaffolds used in tissue engineering.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.