Catalog Number | Size | Price | Quantity | ||
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BADC-00673 | -- | $-- | Inquiry |
CL2 linker is a versatile chemical compound used in bioconjugation and molecular biology applications. Here are some key applications of CL2 linker:
Antibody-Drug Conjugates (ADCs): The CL2 linker is widely used in the development of antibody-drug conjugates, where it connects a cytotoxic drug to an antibody. This linker ensures stable attachment during circulation and releases the drug in a controlled manner upon reaching the target cells. This targeted delivery enhances the therapeutic efficacy while minimizing off-target effects.
Protein-Protein Interactions: CL2 linkers are used to study protein-protein interactions by covalently linking two proteins of interest. By maintaining the spatial orientation and functional integrity of the proteins, researchers can investigate the dynamics and mechanics of their interactions. This is crucial for understanding cellular processes and developing new therapeutic strategies.
Peptide Synthesis: In peptide synthesis, CL2 linkers serve as spacers or connectors between different peptide sequences. They facilitate the assembly of complex peptides and proteins with desired functionalities. These linkers help in maintaining the structural and functional integrity of the synthesized peptides, ensuring they perform their intended biological roles.
Biomolecule Immobilization: CL2 linkers are employed to immobilize biomolecules, such as enzymes or antibodies, onto solid supports for various analytical and diagnostic applications. This immobilization enhances the stability and reusability of the biomolecules, making it easier to conduct repetitive assays. Their use is crucial in creating biosensors and other bioanalytical devices.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.