DBCO-PEG2-NHS ester - CAS 2585653-12-7

DBCO-PEG2-NHS ester - CAS 2585653-12-7 Catalog number: BADC-01658

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing an azide group.

Category
ADCs Linker
Product Name
DBCO-PEG2-NHS ester
CAS
2585653-12-7
Catalog Number
BADC-01658
Molecular Formula
C30H31N3O8
Molecular Weight
561.58
DBCO-PEG2-NHS ester

Ordering Information

Catalog Number Size Price Quantity
BADC-01658 -- $-- Inquiry
Description
DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing an azide group.
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[[4-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-4-oxobutanoyl]amino]ethoxy]ethoxy]propanoate
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCNC(=O)CCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42
InChI
InChI=1S/C30H31N3O8/c34-26(31-16-18-40-20-19-39-17-15-30(38)41-33-28(36)13-14-29(33)37)11-12-27(35)32-21-24-7-2-1-5-22(24)9-10-23-6-3-4-8-25(23)32/h1-8H,11-21H2,(H,31,34)
InChIKey
WEMCNVHTFXFLHG-UHFFFAOYSA-N
Appearance
Yellow to brown Oil
Shipping
Ambient temperature
Storage
-20°C

DBCO-PEG2-NHS ester is a bifunctional reagent widely used for bioconjugation applications. Here are some key applications of DBCO-PEG2-NHS ester:

Protein Labeling: DBCO-PEG2-NHS ester facilitates the covalent attachment of proteins to a variety of surfaces or other biomolecules via click chemistry. By reacting with amine groups on proteins, researchers can achieve site-specific labeling without compromising protein function. This technique is essential for studying protein localization, interactions, and dynamics in complex biological systems.

Drug Delivery Systems: DBCO-PEG2-NHS ester is instrumental in the development of targeted drug delivery systems. By conjugating therapeutic agents to targeting ligands through PEG linkers, it ensures efficient and specific delivery to diseased tissues. This approach improves the therapeutic index of drugs and reduces off-target effects.

Biosensor Development: In biosensor technology, DBCO-PEG2-NHS ester is used to immobilize biomolecules on sensor surfaces. This enables the creation of highly sensitive and specific detection platforms for various analytes, including proteins, nucleic acids, and small molecules. Such biosensors are valuable in diagnostics, environmental monitoring, and food safety.

Surface Modification: DBCO-PEG2-NHS ester is utilized to modify the surfaces of nanoparticles, beads, and other materials to enhance their biocompatibility and functionality. By attaching bioligands or antifouling agents, these modified surfaces exhibit improved performance in biomedical applications such as imaging, biosensing, and therapeutics. This helps ensure that the materials interact with biological systems in a predictable and favorable manner.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Why Choose BOC Sciences?

Customer Support

Providing excellent 24/7 customer service and support

Project Management

Offering 100% high-quality services at all stages

Quality Assurance

Ensuring the quality and reliability of products or services

Global Delivery

Ensuring timely delivery of products worldwide

Questions & Comments
Verification code
Send Inquiry
Verification code
Resources & Supports
Inquiry Basket