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N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01111 | -- | $-- |
Azido-PEG3-t-butyl ester, a versatile chemical compound with diverse applications in bioscience research and industrial processes, is explored here with a high degree of perplexity and burstiness:
Bioconjugation: Positioned at the forefront of biotechnological advancements, Azido-PEG3-t-butyl ester serves as a cornerstone in bioconjugation techniques, where biomolecules such as proteins and antibodies are intricately linked using click chemistry reactions. The azide group facilitates precise and potent binding with alkyne-tagged molecules, instrumental in crafting conjugates essential for diagnostics, therapeutic agents, and biosensors with unparalleled precision and efficacy.
Drug Delivery Systems: Acting as a pivotal catalyst in the realm of drug delivery systems, this compound assumes a crucial role as a linker or spacer molecule, elevating the design of advanced drug delivery platforms. Its PEG moiety not only enhances the solubility and biocompatibility of drug carriers, but also elevates the pharmacokinetics and targeting capabilities of therapeutic agents.
Surface Modification: In the sphere of surface modification, Azido-PEG3-t-butyl ester emerges as a key player in enhancing the biocompatibility of nanoparticles, medical devices, and various materials, while simultaneously minimizing non-specific binding to optimize performance. This transformative technology is pivotal in shaping the landscape of cutting-edge biomedical devices like implants and diagnostic tools. By attaching biomolecules to surfaces, researchers can engineer materials with bespoke properties to meet precise application requirements.
Chemical Biology: Delving deep into the realms of chemical biology research, Azido-PEG3-t-butyl ester emerges as a beacon of innovation, pivotal in labeling and monitoring biomolecules within intricate biological systems. The azide group’s unique chemistry enables subsequent reactions with fluorescent or affinity probes via click chemistry, providing a crucial toolkit for investigating protein interactions, cellular uptake mechanisms, and the precise localization of biological macromolecules within live cells and tissues.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
